齊拉西酮

??【編號(hào)】：125730

??【產(chǎn)品名稱(chēng)】：齊拉西酮

??【規(guī)格】：10MG

??【用途】：

　　齊拉西酮

　　Product Name： Ziprasidone

　　CAS號(hào)：146939-27-7

　　分子式：C21H21ClN4OS

　　分子量：412.94

　　貯存：儲(chǔ)存溫度-20°C

　　可溶性： DMSO

　　生化和生理學(xué)機(jī)理：

　　Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects in preclinical assays predictive of antipsychotic activity. Whereas Ziprasidone is a dopamine antagonist in vitro and in vivo, its most potent action is antagonism of 5-HT2A receptors, where its affinity is an order of magnitude greater than that observed for dopamine D2 sites. Additionally, Ziprasidone inhibits neuronal uptake of 5-HT and norepinephrine comparable to the antidepressant imipramine. Ziprasidone differs from other atypical antipsychotic drugs in several clinically important ways, although further experience is necessary to clarify the significance of these differences.

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齊拉西酮

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齊拉西酮

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