XMD8-92, ≥99%
| ??【編號】：125609 ??【產(chǎn)品名稱】：XMD8-92, ≥99% ??【規(guī)格】：10MG ??【用途】：   XMD8-92, ≥99%
Product Name： XMD8-92
CAS號：1234480-50-2
分子式：C26H30N6O3
分子量：474.57
貯存： 儲存溫度-20°C
可溶性： DMSO
生化和生理學(xué)機理：
XMD8-92 is highly selective ERK5/BMK1 inhibitor (KD values are 80, 190, 600 and 890 nM for BMK1, DCAMKL2, PLK4 and TNK1 respectively). XMD8-92 displays selectivity over 402 diverse kinases. XMD8-92 blocks growth factor-induced activation of cellular BMK1 and reduces BMK1 activity in in vitro kinase assays. XMD8-92 also reduces BMK1-dependent transactivating activity of MEF2C. XMD8-92 inhibits proliferation in a variety of cancer cell lines; blocks tumor cell proliferation and tumor-associated angiogenesis.
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| 上一篇：XL335, ≥99% | 下一篇：XL-147, ≥98% |
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