他米巴羅汀，≥99％
Product Name： Tamibarotene
別名：4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoicacid
CAS號(hào)：94497-51-5
分子式：C22H25NO3
分子量：351.44
介紹： Tamibarotene
貯存： 儲(chǔ)存溫度-20°C
可溶性：
DMSO 70 mg/mL
Water <1 mg/mL
Ethanol 70 mg/mL
生化和生理學(xué)機(jī)理：
Tamibarotene, Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Tamibarotene exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.
