QL-IX-55
| ??【編號】：128082 ??【產品名稱】：QL-IX-55 ??【規格】：5MG ??【用途】：   QL-IX-55
Product Name： QL-IX-55
CAS號：1223002-54-7
分子式：C24H14F4N4O
分子量：450.39貯存： 儲存溫度-20°C
可溶性： DMSO
生化和生理學機理：
The functional target of QL-IX-55 is the ATP-binding site of TOR2 as evidenced by the discovery of resistant alleles of TOR2 through rational design and unbiased selection strategies. QL-IX-55 is capable of potently inhibiting both TOR complex 1 and 2 (TORC1 and TORC2) as demonstrated by biochem. IP kinase assays (IC50 <50 nM) and cellular assays for inhibition of substrate YPK1 phosphorylation. In contrast to rapamycin, QL-IX-55 is capable of inhibiting TORC2-dependent transcription, which suggests that this compd. will be a powerful probe to dissect the Tor2/TORC2-related signaling pathway in yeast.
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| 上一篇：喹硫平 | 下一篇：RI-1, ≥99% |
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