MMAD, ≥99%
| ??【編號】：125063 ??【產品名稱】：MMAD, ≥99% ??【規格】：5MG ??【用途】：   MMAD, ≥99%
Product Name： MMAD
CAS號：203849-91-6
分子式：C41H66N6O6S
分子量：771.06
貯存： 儲存溫度-20°C
可溶性： 25°C： DMSO
生化和生理學機理：
Description：
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate.
For comparison purposes, the ADC A1 -mc-MMAD and/or A1 -vc-MMAD were used. The linker payload, mc-MMAD (6-maleimidocaproyl-monomethylauristatin-D) was conjugated to the A1 anti-5T4 monoclonal antibody through a cysteine residue at a ratio of approximately 4 drug moieties per antibody molecule. The linker payload mc- Val-Cit-PABA-MMAD or vc-MMAD (maleimidocapronic -valine-citruline-p- aminobenzyloxycarbonyl- monomethylauristatin-D) was conjugated to the A1 anti-5T4 monoclonal antibody through a cysteine residue at a ratio of approximately 4 drug moieties per antibody molecule (Antibody-drug conjugates Patent： WO 2013068874 A1).
|
| 上一篇：JANEX-1 | 下一篇：Tipranavir, ≥99% |
|---|
熱銷產品 新品上架
產品推薦 相關產品