超氧化物歧化酶 來源于牛紅細(xì)胞, ≥1,400 units/mg dry weight
??【編號(hào)】:128537 ??【產(chǎn)品名稱】:超氧化物歧化酶 來源于牛紅細(xì)胞, ≥1,400 units/mg dry weight ??【規(guī)格】:2mg ??【用途】: ![]() 超氧化物歧化酶 來源于牛紅細(xì)胞, ≥1,400 units/mg dry weight
Product Name: Superoxide Dismutase from bovine erythrocytes
別名:SOD;超氧化物;超氧化物氧化還原酶
CAS號(hào):9054-89-1
介紹: Superoxide dismutase (SOD) catalyzes the removal of the O2- free radical. The enzyme protects oxygen-metabolizing cells against harmful effects of superoxide free-radicals. Superoxide dismutase is inactivated by H2O2. It consists of two subunits of identical molecular weight joined by a disulfide bond. The molecular weight is 32,500 daltons, and there are two Cu(II) and two Zn(II) atoms per molecule. The isoelectric point of the enzyme is 4.95.
用途: Superoxide dismutase from bovine erythrocytes has been used in a study to assess a kinetic model of radiation-induced inactivation of superoxide dismutase in nitrous oxide-saturated solutions. Superoxide dismutase from bovine erythrocytes has also been used in a study to investigate the possible participation of superoxide anion in the intestinal tryptophan 2,3-dioxygenase reaction.
貯存: 儲(chǔ)存溫度 2-8°C
生化和生理學(xué)機(jī)理: 催化超氧化物自由基的歧化反應(yīng)生成過氧化氫和氧分子。在細(xì)胞防御氧自由基的毒性作用方面發(fā)揮著重要作用。與一氧化氮 (NO) 競(jìng)爭超氧化物陰離子(可與 NO 反應(yīng)形成過亞硝酸鹽),因此 SOD 能促進(jìn) NO 的活性。在培養(yǎng)的大鼠卵泡、神經(jīng)細(xì)胞系和轉(zhuǎn)基因小鼠中,SOD 也表現(xiàn)出抑制細(xì)胞凋亡的作用。
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上一篇:核糖核酸酶 B 來源于牛胰腺, ≥1,000 units/mg dry weight | 下一篇:酪氨酸酶 來源于菌菇, ≥500 units/mg dry weight |
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