大鼠骨肉瘤細(xì)胞UMR-106

??【編號】：UMR-106

??【名稱】：大鼠骨肉瘤細(xì)胞UMR-106

??【規(guī)格】：株

??【價(jià)格】：2300

　　大鼠骨肉瘤細(xì)胞

　　細(xì)胞名稱：UMR-106大鼠骨肉瘤細(xì)胞

　　描述：注射放射性同位素磷(32P)誘導(dǎo)產(chǎn)生的可移植性大鼠骨肉瘤克隆建立了UMR-106細(xì)胞株。細(xì)胞對PTH，前列腺素及破骨甾體有響應(yīng)。對PTH的響應(yīng)度，UMR-106比相關(guān)細(xì)胞株UMR-108(ATCC CRL-1663)要高。蛋白激酶C的活化抑制ATP誘導(dǎo)的胞內(nèi)鈣水平的升高。起始骨肉瘤和克隆株都是University of Sheffield的T.J. Martin建立的。

　　種別：大鼠

　　性別：未知

　　組織來源：器官: 骨骼品系: Sprague-Dawley 疾病: 骨肉瘤

　　形態(tài)：上皮細(xì)胞

　　培養(yǎng)基和添加劑：DMEM培養(yǎng)基(GIBCO,貨號12800017，添加NaHCO3 1.5g/L)，90%；優(yōu)質(zhì)胎牛血清，10%。氣相：空氣，95%；二氧化碳，5%。溫度：37攝氏度。

　　供應(yīng)限制：A。僅供研究之用。

　　REFERENCE：Banerjee C, et al. An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteoclacin gene. Proc. Natl. Acad. Sci. USA 93: 4968-4973, 1996. PubMed: 8643513 Endocrinology of calcium metabolism. Amsterdam: Elsevier/North Holland; 1977. Atkins D, et al. Rat osteogenic sarcoma cells: modulation of hormone stimulated cyclic AMP production by prostaglandin antagonists and biosynthesis inhibitors. Clin. Exp. Pharmacol. Physiol. 7: 31-44, 1980. PubMed: 6103768 Manolagas SC, Deftos LJ. Cytoreceptor assay for 1,25-dihydroxyvitamin D3: a novel radiometric method based on binding of the hormone to intracellular receptors in vitro. Lancet 2: 401-402, 1980. PubMed: 6105521 Partridge NC, et al. Receptors for 1,25(OH)2-vitamin D3 enriched in cloned osteoblast-like rat osteogenic sarcoma cells. FEBS Lett. 115: 139-142, 1980. PubMed: 6248375 Ingleton PM, et al. Alkaline phosphatase in serum and tumour of rats bearing a hormone- responsive transplantable osteogenic sarcoma. Eur. J. Cancer 15: 685-691, 1979. PubMed: 292595 Crawford A, et al. Membranes from a transplantable osteogenic sarcoma responsive to parathyroid hormone and prostaglandins: regulation of adenylate cyclase and of hormone metabolism. J. Endocrinol. 77: 213-224, 1978. PubMed: 275436 Atkins D, Martin TJ. Rat osteogenic sarcoma cells:effects of some prostaglandins, their metabolites and analogues on cyclic AMP production. Prostaglandins 13: 861-871, 1977. PubMed: 194286 Martin TJ, et al. Parathyroid hormone-responsive adenylate cyclase in induced transplantable osteogenic rat sarcoma. Nature 260: 436-438, 1976. PubMed: 1062678 Ingleton PM, et al. Radiation induced osteogenic sarcoma in the rat as a model of hormone-responsive differentiated cancer. Lab. Anim. Sci. 27: 748-756, 1977. PubMed: 338978 Atkins D, et al. Rat osteogenic sarcoma cells: isolation and effects of hormones on the production of cyclic AMP and cyclic GMP. Endocrinology 101: 555-562, 1977. PubMed: 195798 Crawford A, et al. Rat osteogenic sarcoma cells: comparison of the effects of prostaglandins E1, E2, I2 (prostacyclin), 6-keto F1alpha and thromboxane B2 on cyclic AMP production and adenylate cyclase activity. Biochem. Biophys. Res. Commun. 82: 1195-1201, 1978. PubMed: 212039 Gallinaro BJ, et al. Activation of protein kinase C inhibits ATP-induced [Ca2+]I elevation in rat osteoblastic cells: selective effects on P2Y and P2U signaling pathways. J. Cell. Physiol. 162: 305-314, 1995. PubMed: 7860638 Clin. Orthop. Relat. Res. 140: 247-254, 1979. Manolagas SC, et al. 1,25-Dihydroxyvitamin D3 receptor-like macromolecule in rat osteogenic sarcoma cell lines. J. Biol. Chem. 255: 4414-4417, 1980. PubMed: 6929275 Underwood JC, et al. Structural and functional correlations in parathyroid hormone responsive transplantable osteogenic sarcomas. Eur. J. Cancer 15: 1151-1158, 1979. PubMed: 294355 24392: . . Trans. Biochem. Sic. 6: 239-241, 1978. Partridge NC, et al. Morphological and biochemical characterization of four clonal osteogenic sarcoma cell lines of rat origin. Cancer Res. 43: 4308-4315, 1983. PubMed: 6575864 Martin TJ, et al. Hormonal influences on bone cells. Methods Enzymol. 145: 324-336, 1987. PubMed: 3474491 Forrest SM, et al. Characterization of an osteoblast-like clonal cell line which responds to both parathyroid hormone and calcitonin. Calcif. Tissue Int. 37: 51-56, 1985. PubMed: 3922597 Hocking AM, et al. Eukaryotic expression of recombinant biglycan. J. Biol. Chem. 271: 19571-19577, 1996.

上一篇：雞胚成纖維細(xì)胞UMNSAH/DF-1		下一篇：人膀胱移行細(xì)胞癌UM-UC-3

大鼠骨肉瘤細(xì)胞

產(chǎn)品明細(xì)

熱銷產(chǎn)品 新品上架

產(chǎn)品推薦 相關(guān)產(chǎn)品

大鼠骨肉瘤細(xì)胞

產(chǎn)品明細(xì)

熱銷產(chǎn)品 新品上架

產(chǎn)品推薦 相關(guān)產(chǎn)品

　　大鼠骨肉瘤細(xì)胞

熱銷產(chǎn)品新品上架

產(chǎn)品推薦相關(guān)產(chǎn)品